Welcome

Protelica is a proven pioneer in the field of high-throughput protein engineering and optimization. Building upon our extensive patented technology, we’re applying the latest advances in evolutionary mutagenesis to develop therapeutics that address critical, unmet medical needs.

Our principal focus is to develop superior next generation, protein-based therapeutics including hormones, cytokines and enzymes. We utilize targeted, site-directed mutagenesis, systematically mapping the most important residues for inclusion in combinatorial mutagenesis, resulting in identification of the best candidates.

Protelica patented technology platform is based on Dr. Roberto Crea´s Walk-Through Mutagenesis™ and Look-Through Mutagenesis™, which accelerate protein evolution. We’re able to generate and screen diverse libraries of high information and sequence space by integrating these mutagenesis technologies with a proprietary bioinformatics knowledge database of structure/function relationships, computational homology and biological relevance.